New approach for treating neuropathic pain

Neuropathic pain is the chronic, pathological pain that continues even when the cause of pain is removed. Causes include damage to nerve cells and medicines used to treat cancer. Scientists have discovered a novel therapeutic that appears to interrupt the signaling cascades in the body required for multiple forms of neuropathic pain. Source: Feed4

Gut check: Metabolites shed by intestinal microbiota keep inflammation at bay

Researchers have elucidated a mechanism by which ‘good’ bacteria that reside in our gastrointestinal tract can help protect us from inflammation, and how their disruption (dysbiosis) can increase the susceptibility of the liver to more harmful forms of disease. Their study identified two key metabolites produced by the bacteria in mice that modulate inflammation in […]

Osteoporosis drug could be used to treat aggressive form of breast cancer, researchers say

Researchers have discovered that an enzyme called UGT8 drives the progression of basal-like breast cancer, an aggressive form of the disease that is largely untreatable. But the study reveals that the widely used osteoporosis drug zoledronic acid inhibits UGT8 and prevents the spread of basal-like breast cancer in mice, suggesting that this drug could also […]