'Matching' DNA could make for healthier 3-parent babies: study

Nuclear DNA is transfer to offspring by both the father and mother, but mitochondrial DNA is inherited from the mother aloneBetter matching the DNA of egg donors and recipient mothers-to-be may limit the risk of transferring disease-causing mutations to so-called three-parent babies, a study suggested Wednesday. While further work is needed, the study adds to the fast-growing field of in-vitro fertilisation for women with damaged mitochondrial DNA (mtDNA) — the type inherited solely from our mothers. An egg donor — the third parent along with the couple who go on to give birth to and raise a baby — should be selected whose mtDNA is genetically closely related to that of the recipient mother, the authors wrote in the journal Nature.

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